Tris(2-carboxyethyl)phosphine Hydrochloride (TCEP HCl): Product Overview, Applications, Market Analysis, and Future Prospects
Product Overview
Chemical Name: Tris(2-carboxyethyl)phosphine Hydrochloride (TCEP HCl)
Synonyms: TCEP HCl, TCEP Hydrochloride
CAS Number: 51805-45-9
Molecular Formula: C9H15ClO6P·HCl
Appearance: White to off-white crystalline powder
Key Features:
Strong Reducing Agent: Efficiently cleaves disulfide bonds in proteins and peptides without generating toxic byproducts.
Water-Soluble: Easily dissolves in aqueous solutions for biochemical applications.
Stability: Maintains activity under neutral to slightly acidic conditions.
High Purity: ≥98% purity, ideal for research and industrial use.
Storage: Store at 2–8°C in a dry, dark environment.
Applications
Biochemistry & Molecular Biology
Protein Research: Reduces disulfide bonds in protein structure analysis (e.g., SDS-PAGE, mass spectrometry).
Nucleic Acid Studies: Prevents oxidation in RNA/DNA handling.
Enzyme Activity Preservation: Stabilizes enzymes by maintaining reduced states.
Pharmaceuticals
Drug Formulation: Protects therapeutic proteins and antibodies from oxidation.
Bioconjugation: Facilitates controlled crosslinking in antibody-drug conjugates (ADCs).
Material Science
Polymer Modification: Acts as a reducing agent in synthesizing functional polymers.
Nanoparticle Stabilization: Prevents aggregation in nanomaterial synthesis.
Diagnostics
In Vitro Assays: Enhances accuracy in diagnostic kits by reducing sample oxidation.
Market Analysis
Current Market Trends:
The global TCEP HCl market is projected to grow at a CAGR of 6.2% (2023–2028) driven by rising demand in biopharmaceuticals and diagnostics.
Key sectors: Biotech R&D, Drug Development, and Academic Research.
Growth Drivers:
Biopharma Expansion: Increasing use of monoclonal antibodies and protein-based therapies.
Personalized Medicine: Demand for precise diagnostic tools and targeted therapies.
Sustainable Chemistry: Shift toward non-toxic reducing agents in green chemistry.
Regional Insights:
North America: Dominates due to advanced biotech infrastructure (40% market share).
Asia-Pacific: Fastest-growing region with rising R&D investments in China and India.
Competitive Landscape:
Leading suppliers: Thermo Fisher Scientific, Merck KGaA, Tokyo Chemical Industry (TCI).
Opportunities for niche players in high-purity and custom formulations.
Future Application Scenarios
Gene Therapy
Stabilize CRISPR-Cas9 components during gene editing processes.
Advanced Nanomedicine
Enable precise synthesis of drug-loaded nanoparticles for targeted delivery.
3D Bioprinting
Maintain redox balance in bioinks for tissue engineering.
Sustainable Industrial Processes
Replace toxic reductants (e.g., DTT) in eco-friendly manufacturing.
AI-Driven Drug Discovery
Integrate with automated platforms for high-throughput screening.
Why Choose Our TCEP HCl?
Certified Quality: ISO 9001 compliant with batch-specific COA.
Custom Packaging: Available in 1g to 1kg scales.
Technical Support: Dedicated team for application optimization.
Contact Us Today for competitive pricing and tailored solutions in biochemistry and beyond!
